At the Department of Surgery, College of Medicine, Chungnam National University, from Jan. 1990 to Sept. 1991, Twenty-eight patients with breast cancer were treated with the primary chemotherapy with 3 cycles of FAC regimen before and after
surgery.
After primary chemotherapy, All patients were performed to quadrantectomy and axillary dissection with adjuvant chemotherapy and, or, radiotherapy, tamoxifen.
After the primary chemotherapy with FAC regimen, the largest diameter of the tumor was decreased less than 5 cm. The most common location of breast cancer was in the upper outer quadrant(18/25).
Among 28 cases, 18 cases were performed to radial incision, 10 cases were curvilinear incision and in axillary incision, 13 cases were separate and 15 cases were non-separate incision from breast incision.
After the quadrantectomy and axillary dissection, 23 cases of among 28 patients with breast cancer were invasive ductal carcinoma and the most common complication was wound seroma (2/28).
In conclusion, The quadrantectomy and axillary dissection may offer an effective alternative to mastectomy for patients with breast cancer after inductive chemotheraphy and merits further study.
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